Table 4.

Bone marrow myelo-erythroid cell distribution and erythropoietin responsiveness to propranolol administration after burn injury

Total Bone Marrow Cell DistributionShamPBD7PBD7 + PRPBD7 + PR + Epo
Ter119+ (erythroid)33.0 ± 2.0%9.0 ± 1.0%*18.0 ± 0.8%*24.0 ± 0.8%*
CD11b+ (myeloid)36.0 ± 2.0%66.0 ± 2.0%*55.0 ± 1.5%*55.0 ± 1.2%*
  • Values are means ± SE. Experiments repeated 3 times with n = 6 mice/group. Improved erythropoietin (Epo) responsiveness was observed with exogenous Epo in propranolol-treated burn mice.

  • * P < 0.0001 vs. Sham;

  • P < 0.0001 vs. PBD7;

  • P < 0.008 vs. PBD7 + PR by one-way ANOVA.