Am J Physiol Cell Physiol -- Table of Contents (July 1 2008, 295 [1])

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EDITORIAL:

Paul A. Insel: AJP-Cell Physiology: the whole is greater than the sum of its parts
Am J Physiol Cell Physiol 295: C1-C1, 2008; doi:10.1152/ajpcell.zh0-5630.2008 [Full Text] [PDF]

MEMBRANE TRANSPORTERS, ION CHANNELS, AND PUMPS:

Tiemin Liu, Bryan Lo, Pam Speight, and Mel Silverman: Transmembrane IV of the high-affinity sodium-glucose cotransporter participates in sugar binding
Am J Physiol Cell Physiol 295: C64-C72, 2008. First published April 30, 2008; doi:10.1152/ajpcell.90602.2007 [Abstract] [Full Text] [PDF]

Friderike Schuetz, Sharad Kumar, Philip Poronnik, and David J. Adams: Regulation of the voltage-gated K⁺ channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1
Am J Physiol Cell Physiol 295: C73-C80, 2008. First published May 7, 2008; doi:10.1152/ajpcell.00146.2008 [Abstract] [Full Text] [PDF]

Boyi Liu, Huiling Liang, Li Liu, and Hailin Zhang: Phosphatidylinositol 4,5-bisphosphate hydrolysis mediates histamine-induced KCNQ/M current inhibition
Am J Physiol Cell Physiol 295: C81-C91, 2008. First published April 30, 2008; doi:10.1152/ajpcell.00028.2008 [Abstract] [Full Text] [PDF]

Donghee Kim, Eric J. Cavanaugh, and Dina Simkin: Inhibition of transient receptor potential A1 channel by phosphatidylinositol-4,5-bisphosphate
Am J Physiol Cell Physiol 295: C92-C99, 2008. First published May 21, 2008; doi:10.1152/ajpcell.00023.2008 [Abstract] [Full Text] [PDF]

Amritlal Mandal, Nicholas A. Delamere, and Mohammad Shahidullah: Ouabain-induced stimulation of sodium-hydrogen exchange in rat optic nerve astrocytes
Am J Physiol Cell Physiol 295: C100-C110, 2008. First published April 30, 2008; doi:10.1152/ajpcell.90636.2007 [Abstract] [Full Text] [PDF]

Beiyun Zhou, David K. Ann, Per Flodby, Parviz Minoo, Janice M. Liebler, Edward D. Crandall, and Zea Borok: Rat aquaporin-5 4.3-kb 5'-flanking region differentially regulates expression in salivary gland and lung in vivo
Am J Physiol Cell Physiol 295: C111-C120, 2008. First published April 30, 2008; doi:10.1152/ajpcell.90620.2007 [Abstract] [Full Text] [PDF]

Gavin S. Stewart, Jennifer H. O'Brien, and Craig P. Smith: Ubiquitination regulates the plasma membrane expression of renal UT-A urea transporters
Am J Physiol Cell Physiol 295: C121-C129, 2008. First published April 30, 2008; doi:10.1152/ajpcell.00444.2007 [Abstract] [Full Text] [PDF]

Francesca Sbrana, Chiara Sassoli, Elisabetta Meacci, Daniele Nosi, Roberta Squecco, Ferdinando Paternostro, Bruno Tiribilli, Sandra Zecchi-Orlandini, Fabio Francini, and Lucia Formigli: Role for stress fiber contraction in surface tension development and stretch-activated channel regulation in C2C12 myoblasts
Am J Physiol Cell Physiol 295: C160-C172, 2008. First published May 14, 2008; doi:10.1152/ajpcell.00014.2008 [Abstract] [Full Text] [PDF]

MUSCLE CELL BIOLOGY AND CELL MOTILITY:

Rainer Ng, Joseph M. Metzger, Dennis R. Claflin, and John A. Faulkner: Poloxamer 188 reduces the contraction-induced force decline in lumbrical muscles from mdx mice
Am J Physiol Cell Physiol 295: C146-C150, 2008. First published May 21, 2008; doi:10.1152/ajpcell.00017.2008 [Abstract] [Full Text] [PDF] [Supplemental Figure]

E. P. Debold, S. E. Beck, and D. M. Warshaw: Effect of low pH on single skeletal muscle myosin mechanics and kinetics
Am J Physiol Cell Physiol 295: C173-C179, 2008. First published May 14, 2008; doi:10.1152/ajpcell.00172.2008 [Abstract] [Full Text] [PDF]

Matthew P. Krause, Ying Liu, Vivian Vu, Lawrence Chan, Aimin Xu, Michael C. Riddell, Gary Sweeney, and Thomas J. Hawke: Adiponectin is expressed by skeletal muscle fibers and influences muscle phenotype and function
Am J Physiol Cell Physiol 295: C203-C212, 2008. First published May 7, 2008; doi:10.1152/ajpcell.00030.2008 [Abstract] [Full Text] [PDF]

Gordon S. Lynch, John A. Faulkner, and Susan V. Brooks: Force deficits and breakage rates after single lengthening contractions of single fast fibers from unconditioned and conditioned muscles of young and old rats
Am J Physiol Cell Physiol 295: C249-C256, 2008. First published May 28, 2008; doi:10.1152/ajpcell.90640.2007 [Abstract] [Full Text] [PDF]

RECEPTORS AND SIGNAL TRANSDUCTION:

Karina Thieme, Débora Mai N. Eguti, Margarida Mello-Aires, and Maria Oliveira-Souza: The effect of angiotensin II on intracellular pH is mediated by AT₁ receptor translocation
Am J Physiol Cell Physiol 295: C138-C145, 2008. First published April 23, 2008; doi:10.1152/ajpcell.00512.2007 [Abstract] [Full Text] [PDF]

Andrew E. Blum, Sheldon M. Joseph, Ronald J. Przybylski, and George R. Dubyak: Rho-family GTPases modulate Ca²⁺-dependent ATP release from astrocytes
Am J Physiol Cell Physiol 295: C231-C241, 2008. First published May 21, 2008; doi:10.1152/ajpcell.00175.2008 [Abstract] [Full Text] [PDF]

Takayuki Akimoto, Ping Li, and Zhen Yan: Functional interaction of regulatory factors with the Pgc-1 ${alpha}$ promoter in response to exercise by in vivo imaging
Am J Physiol Cell Physiol 295: C288-C292, 2008. First published April 23, 2008; doi:10.1152/ajpcell.00104.2008 [Abstract] [Full Text] [PDF]

VASCULAR BIOLOGY:

Charles I. Jones, III, Zhaosheng Han, Tennille Presley, Saradhadevi Varadharaj, Jay L. Zweier, Govindasamy Ilangovan, and B. Rita Alevriadou: Endothelial cell respiration is affected by the oxygen tension during shear exposure: role of mitochondrial peroxynitrite
Am J Physiol Cell Physiol 295: C180-C191, 2008. First published May 14, 2008; doi:10.1152/ajpcell.00549.2007 [Abstract] [Full Text] [PDF]

Ayako Makino, Oleksandr Platoshyn, Jorge Suarez, Jason X.-J. Yuan, and Wolfgang H. Dillmann: Downregulation of connexin40 is associated with coronary endothelial cell dysfunction in streptozotocin-induced diabetic mice
Am J Physiol Cell Physiol 295: C221-C230, 2008. First published May 7, 2008; doi:10.1152/ajpcell.00433.2007 [Abstract] [Full Text] [PDF]

Philippe G. Frank, Stephanos Pavlides, Michelle W.-C. Cheung, Kristin Daumer, and Michael P. Lisanti: Role of caveolin-1 in the regulation of lipoprotein metabolism
Am J Physiol Cell Physiol 295: C242-C248, 2008. First published May 28, 2008; doi:10.1152/ajpcell.00185.2008 [Abstract] [Full Text] [PDF]

Yuchuan Liu, Dian J. Cao, Irma M. Sainz, Yan-Lin Guo, and Robert W. Colman: The inhibitory effect of HKa in endothelial cell tube formation is mediated by disrupting the uPA-uPAR complex and inhibiting its signaling and internalization
Am J Physiol Cell Physiol 295: C257-C267, 2008. First published May 21, 2008; doi:10.1152/ajpcell.00569.2007 [Abstract] [Full Text] [PDF]

GROWTH, DIFFERENTIATION, AND APOPTOSIS:

Behnam Saberi, Mie Shinohara, Maria D. Ybanez, Naoko Hanawa, William A. Gaarde, Neil Kaplowitz, and Derick Han: Regulation of H₂O₂-induced necrosis by PKC and AMP-activated kinase signaling in primary cultured hepatocytes
Am J Physiol Cell Physiol 295: C50-C63, 2008. First published May 7, 2008; doi:10.1152/ajpcell.90654.2007 [Abstract] [Full Text] [PDF]

Fei Wang and Qiang Tong: Transcription factor PU.1 is expressed in white adipose and inhibits adipocyte differentiation
Am J Physiol Cell Physiol 295: C213-C220, 2008. First published May 7, 2008; doi:10.1152/ajpcell.00422.2007 [Abstract] [Full Text] [PDF]

PROTEIN AND VESICLE TRAFFICKING, CYTOSKELETON:

Nitza Lahat, Michal A. Rahat, Amalia Kinarty, Lea Weiss-Cerem, Sigalit Pinchevski, and Haim Bitterman: Hypoxia enhances lysosomal TNF- ${alpha}$ degradation in mouse peritoneal macrophages
Am J Physiol Cell Physiol 295: C2-C12, 2008. First published April 23, 2008; doi:10.1152/ajpcell.00572.2007 [Abstract] [Full Text] [PDF]

Ronald R. Marchelletta, Damon T. Jacobs, Joel E. Schechter, Richard E. Cheney, and Sarah F. Hamm-Alvarez: The class V myosin motor, myosin 5c, localizes to mature secretory vesicles and facilitates exocytosis in lacrimal acini
Am J Physiol Cell Physiol 295: C13-C28, 2008. First published April 23, 2008; doi:10.1152/ajpcell.00330.2007 [Abstract] [Full Text] [PDF] [Supplemental Figure]

Lixin Zhu, Jason Hatakeyama, Cheng Chen, Aditi Shastri, Kevin Poon, and John G. Forte: Comparative study of ezrin phosphorylation among different tissues: more is good; too much is bad
Am J Physiol Cell Physiol 295: C192-C202, 2008. First published May 14, 2008; doi:10.1152/ajpcell.00159.2008 [Abstract] [Full Text] [PDF]

Chunlei Huan, Kai Su Greene, Bo Shui, Gwendolyn Spizz, Haitao Sun, Robert M. Doran, Patricia J. Fisher, Mark S. Roberson, Randolph C. Elble, and Michael I. Kotlikoff: mCLCA4 ER processing and secretion requires luminal sorting motifs
Am J Physiol Cell Physiol 295: C279-C287, 2008. First published May 21, 2008; doi:10.1152/ajpcell.00060.2008 [Abstract] [Full Text] [PDF]

EXTRACELLULAR MATRIX, CELL INTERACTIONS:

Kamal S. Gill, Frank Beier, and Harvey A. Goldberg: Rho-ROCK signaling differentially regulates chondrocyte spreading on fibronectin and bone sialoprotein
Am J Physiol Cell Physiol 295: C38-C49, 2008. First published May 7, 2008; doi:10.1152/ajpcell.00548.2007 [Abstract] [Full Text] [PDF]

P. D. Arora, P. A. Marignani, and C. A. McCulloch: Collagen phagocytosis is regulated by the guanine nucleotide exchange factor Vav2
Am J Physiol Cell Physiol 295: C130-C137, 2008. First published April 23, 2008; doi:10.1152/ajpcell.00168.2008 [Abstract] [Full Text] [PDF]

Dustin A. Dikeman, Leslie A. Rivera Rosado, Troy A. Horn, Christina S. Alves, Konstantinos Konstantopoulos, and Joy T. Yang: ${alpha}$ ₄β₁-Integrin regulates directionally persistent cell migration in response to shear flow stimulation
Am J Physiol Cell Physiol 295: C151-C159, 2008. First published May 21, 2008; doi:10.1152/ajpcell.00169.2008 [Abstract] [Full Text] [PDF] [Supplemental Videos]

Zhe Sun, Luis A. Martinez-Lemus, Michael A. Hill, and Gerald A. Meininger: Extracellular matrix-specific focal adhesions in vascular smooth muscle produce mechanically active adhesion sites
Am J Physiol Cell Physiol 295: C268-C278, 2008. First published May 21, 2008; doi:10.1152/ajpcell.00516.2007 [Abstract] [Full Text] [PDF]

CELLULAR AND MITOCHONDRIAL METABOLISM:

Vijayalakshmi Sridharan, Jason Guichard, Chuan-Yuan Li, Robin Muise-Helmericks, Craig Cano Beeson, and Gary L. Wright: O₂-sensing signal cascade: clamping of O₂ respiration, reduced ATP utilization, and inducible fumarate respiration
Am J Physiol Cell Physiol 295: C29-C37, 2008. First published May 7, 2008; doi:10.1152/ajpcell.00466.2007 [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Cover: Coimmunofluorescence analysis of β-catenin (green) and actin (red) in migrating human corneal epithelial cells showing continuous cortical actin network and uninterrupted β-catenin structure at cell-cell junction. From: Yin J and Yu FS. “Rho kinases regulate corneal epithelial wound healing.” Am J Physiol Cell Physiol (May 21, 2008). doi:10.1152/ajpcell.90624.2007.