Am J Physiol Cell Physiol -- Table of Contents (February 1 2008, 294 [2])

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EDITORIAL FOCUS:

James F. Collins: Novel insights into intestinal and renal folate transport. Focus on "Apical membrane targeting and trafficking of the human proton-coupled folate transporter in polarized epithelia"
Am J Physiol Cell Physiol 294: C381-C382, 2008. First published December 5, 2007; doi:10.1152/ajpcell.00566.2007 [Full Text] [PDF]

MEMBRANE TRANSPORTERS, ION CHANNELS, AND PUMPS:

Bret A. Hughes and Anuradha Swaminathan: Modulation of the Kir7.1 potassium channel by extracellular and intracellular pH
Am J Physiol Cell Physiol 294: C423-C431, 2008. First published December 19, 2007; doi:10.1152/ajpcell.00393.2007 [Abstract] [Full Text] [PDF]

Bryan Mackenzie, Anthony C. Illing, and Matthias A. Hediger: Transport model of the human Na⁺-coupled L-ascorbic acid (vitamin C) transporter SVCT1
Am J Physiol Cell Physiol 294: C451-C459, 2008. First published December 19, 2007; doi:10.1152/ajpcell.00439.2007 [Abstract] [Full Text] [PDF]

Núria M. Pastor-Soler, Kenneth R. Hallows, Christy Smolak, Fan Gong, Dennis Brown, and Sylvie Breton: Alkaline pH- and cAMP-induced V-ATPase membrane accumulation is mediated by protein kinase A in epididymal clear cells
Am J Physiol Cell Physiol 294: C488-C494, 2008. First published December 26, 2007; doi:10.1152/ajpcell.00537.2007 [Abstract] [Full Text] [PDF]

Angela Goytain and Gary A. Quamme: Identification and characterization of a novel family of membrane magnesium transporters, MMgT1 and MMgT2
Am J Physiol Cell Physiol 294: C495-C502, 2008. First published December 5, 2007; doi:10.1152/ajpcell.00238.2007 [Abstract] [Full Text] [PDF]

Jingbo Huang, Leif Hove-Madsen, and Glen F. Tibbits: Ontogeny of Ca²⁺-induced Ca²⁺ release in rabbit ventricular myocytes
Am J Physiol Cell Physiol 294: C516-C525, 2008. First published December 19, 2007; doi:10.1152/ajpcell.00417.2007 [Abstract] [Full Text] [PDF] [Supplemental Figures]

Hisayoshi Hayashi, Orit Aharonovitz, R. Todd Alexander, Nicolas Touret, Wendy Furuya, John Orlowski, and Sergio Grinstein: Na⁺/H⁺ exchange and pH regulation in the control of neutrophil chemokinesis and chemotaxis
Am J Physiol Cell Physiol 294: C526-C534, 2008. First published December 19, 2007; doi:10.1152/ajpcell.00219.2007 [Abstract] [Full Text] [PDF]

Zhaohong Yin, Yiai Tong, Haiqing Zhu, and Mitchell A. Watsky: ClC-3 is required for LPA-activated Cl^– current activity and fibroblast-to-myofibroblast differentiation
Am J Physiol Cell Physiol 294: C535-C542, 2008. First published December 12, 2007; doi:10.1152/ajpcell.00291.2007 [Abstract] [Full Text] [PDF]

Haiping Cai, Liang Wu, Weikai Qu, Deepak Malhotra, Zijian Xie, Joseph I. Shapiro, and Jiang Liu: Regulation of apical NHE3 trafficking by ouabain-induced activation of the basolateral Na⁺-K⁺-ATPase receptor complex
Am J Physiol Cell Physiol 294: C555-C563, 2008. First published December 12, 2007; doi:10.1152/ajpcell.00475.2007 [Abstract] [Full Text] [PDF]

C. N. White, E. J. Hamilton, A. Garcia, D. Wang, K. K. M. Chia, G. A. Figtree, and H. H. Rasmussen: Opposing effects of coupled and uncoupled NOS activity on the Na⁺-K⁺ pump in cardiac myocytes
Am J Physiol Cell Physiol 294: C572-C578, 2008. First published December 5, 2007; doi:10.1152/ajpcell.00242.2007 [Abstract] [Full Text] [PDF]

Youssef Abdul Jalil, Vera Ritz, Ana Jakimenko, Christoph Schmitz-Salue, Heike Siebert, David Awuah, André Kotthaus, Thomas Kietzmann, Christina Ziemann, and Karen I. Hirsch-Ernst: Vesicular localization of the rat ATP-binding cassette half-transporter rAbcb6
Am J Physiol Cell Physiol 294: C579-C590, 2008. First published December 26, 2007; doi:10.1152/ajpcell.00612.2006 [Abstract] [Full Text] [PDF]

Ebbe Boedtkjer, Jeppe Praetorius, Ernst-Martin Füchtbauer, and Christian Aalkjaer: Antibody-independent localization of the electroneutral Na⁺-HCO₃^– cotransporter NBCn1 (slc4a7) in mice
Am J Physiol Cell Physiol 294: C591-C603, 2008. First published December 12, 2007; doi:10.1152/ajpcell.00281.2007 [Abstract] [Full Text] [PDF]

MUSCLE CELL BIOLOGY AND CELL MOTILITY:

Masatoshi Hori, Hiromi Nobe, Kazuhide Horiguchi, and Hiroshi Ozaki: MCP-1 targeting inhibits muscularis macrophage recruitment and intestinal smooth muscle dysfunction in colonic inflammation
Am J Physiol Cell Physiol 294: C391-C401, 2008. First published October 31, 2007; doi:10.1152/ajpcell.00056.2007 [Abstract] [Full Text] [PDF] [Supplemental Table]

Renate J. Scheibe, Karsten Mundhenk, Tilman Becker, Janine Hallerdei, Abdul Waheed, Gul N. Shah, William S. Sly, Gerolf Gros, and Petra Wetzel: Carbonic anhydrases IV and IX: subcellular localization and functional role in mouse skeletal muscle
Am J Physiol Cell Physiol 294: C402-C412, 2008. First published November 14, 2007; doi:10.1152/ajpcell.00228.2007 [Abstract] [Full Text] [PDF]

Minkyung Kim, Grant W. Hennig, Terence K. Smith, and Brian A. Perrino: Phospholamban knockout increases CaM kinase II activity and intracellular Ca²⁺ wave activity and alters contractile responses of murine gastric antrum
Am J Physiol Cell Physiol 294: C432-C441, 2008. First published November 28, 2007; doi:10.1152/ajpcell.00418.2007 [Abstract] [Full Text] [PDF]

Hélène Richard-Bulteau, Bernard Serrurier, Brigitte Crassous, Sébastien Banzet, André Peinnequin, Xavier Bigard, and Nathalie Koulmann: Recovery of skeletal muscle mass after extensive injury: positive effects of increased contractile activity
Am J Physiol Cell Physiol 294: C467-C476, 2008. First published December 12, 2007; doi:10.1152/ajpcell.00355.2007 [Abstract] [Full Text] [PDF]

Giuliana Di Rocco, Alessandra Tritarelli, Gabriele Toietta, Ilaria Gatto, Maria Grazia Iachininoto, Francesca Pagani, Antonella Mangoni, Stefania Straino, and Maurizio C. Capogrossi: Spontaneous myogenic differentiation of Flk-1-positive cells from adult pancreas and other nonmuscle tissues
Am J Physiol Cell Physiol 294: C604-C612, 2008. First published December 19, 2007; doi:10.1152/ajpcell.00383.2007 [Abstract] [Full Text] [PDF] [Supplemental Figures]

Ewa Prochniewicz, Dawn A. Lowe, Daniel J. Spakowicz, LeeAnn Higgins, Kate O'Conor, LaDora V. Thompson, Deborah A. Ferrington, and David D. Thomas: Functional, structural, and chemical changes in myosin associated with hydrogen peroxide treatment of skeletal muscle fibers
Am J Physiol Cell Physiol 294: C613-C626, 2008. First published November 14, 2007; doi:10.1152/ajpcell.00232.2007 [Abstract] [Full Text] [PDF]

Jianming Liu, Dean J. Burkin, and Stephen J. Kaufman: Increasing ${alpha}$ ₇β₁-integrin promotes muscle cell proliferation, adhesion, and resistance to apoptosis without changing gene expression
Am J Physiol Cell Physiol 294: C627-C640, 2008. First published November 28, 2007; doi:10.1152/ajpcell.00329.2007 [Abstract] [Full Text] [PDF] [Supplemental Tables]

Dennis R. Claflin and Susan V. Brooks: Direct observation of failing fibers in muscles of dystrophic mice provides mechanistic insight into muscular dystrophy
Am J Physiol Cell Physiol 294: C651-C658, 2008. First published January 2, 2008; doi:10.1152/ajpcell.00244.2007 [Abstract] [Full Text] [PDF] [Supplemental Videos]

RECEPTORS AND SIGNAL TRANSDUCTION:

Karnam S. Murthy, Sunila Mahavadi, Jiean Huang, Huiping Zhou, and Wimolpak Sriwai: Phosphorylation of GRK2 by PKA augments GRK2-mediated phosphorylation, internalization, and desensitization of VPAC₂ receptors in smooth muscle
Am J Physiol Cell Physiol 294: C477-C487, 2008. First published December 12, 2007; doi:10.1152/ajpcell.00229.2007 [Abstract] [Full Text] [PDF]

VASCULAR BIOLOGY:

Yuan Lu, Haiying Zhang, Natalia Gokina, Maurizio Mandala, Osamu Sato, Mitsuo Ikebe, George Osol, and Steven A. Fisher: Uterine artery myosin phosphatase isoform switching and increased sensitivity to SNP in a rat L-NAME model of hypertension of pregnancy
Am J Physiol Cell Physiol 294: C564-C571, 2008. First published December 19, 2007; doi:10.1152/ajpcell.00285.2007 [Abstract] [Full Text] [PDF]

GROWTH, DIFFERENTIATION, AND APOPTOSIS:

Craig Ricci, Viktor Pastukh, Josh Leonard, Julio Turrens, Glenn Wilson, David Schaffer, and Stephen W. Schaffer: Mitochondrial DNA damage triggers mitochondrial-superoxide generation and apoptosis
Am J Physiol Cell Physiol 294: C413-C422, 2008. First published December 12, 2007; doi:10.1152/ajpcell.00362.2007 [Abstract] [Full Text] [PDF]

PROTEIN AND VESICLE TRAFFICKING, CYTOSKELETON:

Daniel F. Wallace, Lesa Summerville, Emily M. Crampton, and V. Nathan Subramaniam: Defective trafficking and localization of mutated transferrin receptor 2: implications for type 3 hereditary hemochromatosis
Am J Physiol Cell Physiol 294: C383-C390, 2008. First published December 19, 2007; doi:10.1152/ajpcell.00492.2007 [Abstract] [Full Text] [PDF]

David D. Arrington and Rick G. Schnellmann: Targeting of the molecular chaperone oxygen-regulated protein 150 (ORP150) to mitochondria and its induction by cellular stress
Am J Physiol Cell Physiol 294: C641-C650, 2008. First published December 19, 2007; doi:10.1152/ajpcell.00400.2007 [Abstract] [Full Text] [PDF]

EXTRACELLULAR MATRIX, CELL INTERACTIONS:

Sonia Aydin, Sara Signorelli, Thomas Lechleitner, Michael Joannidis, Clara Pleban, Paul Perco, Walter Pfaller, and Paul Jennings: Influence of microvascular endothelial cells on transcriptional regulation of proximal tubular epithelial cells
Am J Physiol Cell Physiol 294: C543-C554, 2008. First published December 5, 2007; doi:10.1152/ajpcell.00307.2007 [Abstract] [Full Text] [PDF]

CELLULAR AND MITOCHONDRIAL METABOLISM:

Michael J. MacDonald, Melissa J. Longacre, Scott W. Stoker, Laura J. Brown, Noaman M. Hasan, and Mindy A. Kendrick: Acetoacetate and β-hydroxybutyrate in combination with other metabolites release insulin from INS-1 cells and provide clues about pathways in insulin secretion
Am J Physiol Cell Physiol 294: C442-C450, 2008. First published December 26, 2007; doi:10.1152/ajpcell.00368.2007 [Abstract] [Full Text] [PDF]

Qun Chen, Shadi Moghaddas, Charles L. Hoppel, and Edward J. Lesnefsky: Ischemic defects in the electron transport chain increase the production of reactive oxygen species from isolated rat heart mitochondria
Am J Physiol Cell Physiol 294: C460-C466, 2008. First published December 12, 2007; doi:10.1152/ajpcell.00211.2007 [Abstract] [Full Text] [PDF]

NERVOUS SYSTEM CELL BIOLOGY:

Paul Smolen, Douglas A. Baxter, and John H. Byrne: Bistable MAP kinase activity: a plausible mechanism contributing to maintenance of late long-term potentiation
Am J Physiol Cell Physiol 294: C503-C515, 2008. First published December 5, 2007; doi:10.1152/ajpcell.00447.2007 [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Cover: Coimmunofluorescence analysis of collagen type I (green) and desmin (red) in differentiated C2C12 after 5 days in differentiation medium showing that collagen type I expression prevents the differentiation of the myoblast cells. From: Alexakis C, Partridge T, and Bou-Gharios G. “Implication of the satellite cell in dystrophic muscle fibrosis: a self-perpetuating mechanism of collagen overproduction.” Am J Physiol Cell Physiol 293: C661–C669, 2007.