Am J Physiol Cell Physiol -- Table of Contents (August 1 2007, 293 [2])

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INVITED REVIEW:

Thomas J. Eddinger and Daniel P. Meer: Myosin II isoforms in smooth muscle: heterogeneity and function
Am J Physiol Cell Physiol 293: C493-C508, 2007. First published May 2, 2007; doi:10.1152/ajpcell.00131.2007 [Abstract] [Full Text] [PDF]

Wilhelm Schoner and Georgios Scheiner-Bobis: Endogenous and exogenous cardiac glycosides: their roles in hypertension, salt metabolism, and cell growth
Am J Physiol Cell Physiol 293: C509-C536, 2007. First published May 9, 2007; doi:10.1152/ajpcell.00098.2007 [Abstract] [Full Text] [PDF]

EDITORIAL FOCUS:

Jeffrey J. Wine: The inexhaustible mouse nose. Focus on "Olfactory epithelia exhibit progressive functional and morphological defects in CF mice"
Am J Physiol Cell Physiol 293: C537-C539, 2007. First published May 16, 2007; doi:10.1152/ajpcell.00183.2007 [Full Text] [PDF]

Stefan Bröer: Lysinuric protein intolerance: one gene, many problems
Am J Physiol Cell Physiol 293: C540-C541, 2007. First published May 2, 2007; doi:10.1152/ajpcell.00166.2007 [Full Text] [PDF]

SPECIAL SECTION ON MITOCHONDRIAL MODELING AND FUNCTION:

Anushka Michailova, William Lorentz, and Andrew McCulloch: Modeling transmural heterogeneity of K_ATP current in rabbit ventricular myocytes
Am J Physiol Cell Physiol 293: C542-C557, 2007. First published February 28, 2007; doi:10.1152/ajpcell.00148.2006 [Abstract] [Full Text] [PDF]

MEMBRANE TRANSPORTERS, ION CHANNELS, AND PUMPS:

Silvia Ravera, Leila V. Virkki, Heini Murer, and Ian C. Forster: Deciphering PiT transport kinetics and substrate specificity using electrophysiology and flux measurements
Am J Physiol Cell Physiol 293: C606-C620, 2007. First published May 9, 2007; doi:10.1152/ajpcell.00064.2007 [Abstract] [Full Text] [PDF]

Krishnaswamy Balamurugan, Balasubramaniem Ashokkumar, Mustapha Moussaif, Ji Ying Sze, and Hamid M. Said: Cloning and functional characterization of a folate transporter from the nematode Caenorhabditis elegans
Am J Physiol Cell Physiol 293: C670-C681, 2007. First published May 2, 2007; doi:10.1152/ajpcell.00516.2006 [Abstract] [Full Text] [PDF]

Haiyan Liu, Judith A. Enyeart, and John J. Enyeart: Angiotensin II inhibits native bTREK-1 K⁺ channels through a PLC-, kinase C-, and PIP₂-independent pathway requiring ATP hydrolysis
Am J Physiol Cell Physiol 293: C682-C695, 2007. First published May 9, 2007; doi:10.1152/ajpcell.00087.2007 [Abstract] [Full Text] [PDF]

Shiho Kaneko, Emiko Okuda-Ashitaka, Akira Ando, Kazuhiro Nishimura, Kazuei Igarashi, Masahide Maeda, Kyoji Furuta, Masaaki Suzuki, Miyo Matsumura, and Seiji Ito: Polyamines upregulate the mRNA expression of cationic amino acid transporter-1 in human retinal pigment epithelial cells
Am J Physiol Cell Physiol 293: C729-C737, 2007. First published May 9, 2007; doi:10.1152/ajpcell.00018.2007 [Abstract] [Full Text] [PDF]

Patricio E. Morgan, Silvia Pastoreková, Alan K. Stuart-Tilley, Seth L. Alper, and Joseph R. Casey: Interactions of transmembrane carbonic anhydrase, CAIX, with bicarbonate transporters
Am J Physiol Cell Physiol 293: C738-C748, 2007. First published July 25, 2007; doi:10.1152/ajpcell.00157.2007 [Abstract] [Full Text] [PDF]

Shigeo Tamiya, Mansim C. Okafor, and Nicholas A. Delamere: Purinergic agonists stimulate lens Na-K-ATPase-mediated transport via a Src tyrosine kinase-dependent pathway
Am J Physiol Cell Physiol 293: C790-C796, 2007. First published May 23, 2007; doi:10.1152/ajpcell.00579.2006 [Abstract] [Full Text] [PDF]

R. Gerometta, A. C. Zamudio, D. P. Escobar, and O. A. Candia: Volume change of the ocular lens during accommodation
Am J Physiol Cell Physiol 293: C797-C804, 2007. First published May 30, 2007; doi:10.1152/ajpcell.00094.2007 [Abstract] [Full Text] [PDF]

MUSCLE CELL BIOLOGY AND CELL MOTILITY:

Joshua N. Edwards, William A. Macdonald, Chris van der Poel, and D. George Stephenson: O₂^– production at 37°C plays a critical role in depressing tetanic force of isolated rat and mouse skeletal muscle
Am J Physiol Cell Physiol 293: C650-C660, 2007. First published April 25, 2007; doi:10.1152/ajpcell.00037.2007 [Abstract] [Full Text] [PDF]

Catherine Alexakis, Terence Partridge, and George Bou-Gharios: Implication of the satellite cell in dystrophic muscle fibrosis: a self-perpetuating mechanism of collagen overproduction
Am J Physiol Cell Physiol 293: C661-C669, 2007. First published May 2, 2007; doi:10.1152/ajpcell.00061.2007 [Abstract] [Full Text] [PDF]

Sheng Zhong and LaDora V. Thompson: The roles of myosin ATPase activity and myosin light chain relative content in the slowing of type IIB fibers with hindlimb unweighting in rats
Am J Physiol Cell Physiol 293: C723-C728, 2007. First published May 9, 2007; doi:10.1152/ajpcell.00009.2007 [Abstract] [Full Text] [PDF]

RECEPTORS AND SIGNAL TRANSDUCTION:

Leif D. Nelin, Xianxi Wang, Qun Zhao, Louis G. Chicoine, Tamara L. Young, Dionna M. Hatch, B. Keith English, and Yusen Liu: MKP-1 switches arginine metabolism from nitric oxide synthase to arginase following endotoxin challenge
Am J Physiol Cell Physiol 293: C632-C640, 2007. First published April 18, 2007; doi:10.1152/ajpcell.00137.2006 [Abstract] [Full Text] [PDF]

J. Fisher, K. Devraj, J. Ingram, B. Slagle-Webb, A. B. Madhankumar, X. Liu, M. Klinger, I. A. Simpson, and J. R. Connor: Ferritin: a novel mechanism for delivery of iron to the brain and other organs
Am J Physiol Cell Physiol 293: C641-C649, 2007. First published April 25, 2007; doi:10.1152/ajpcell.00599.2006 [Abstract] [Full Text] [PDF]

Jia Sun, Raina Devi Ramnath, and Madhav Bhatia: Neuropeptide substance P upregulates chemokine and chemokine receptor expression in primary mouse neutrophils
Am J Physiol Cell Physiol 293: C696-C704, 2007. First published May 9, 2007; doi:10.1152/ajpcell.00060.2007 [Abstract] [Full Text] [PDF]

Christian Rosker, Birgit Lohberger, Doris Hofer, Bibiane Steinecker, Stefan Quasthoff, and Wolfgang Schreibmayer: The TTX metabolite 4,9-anhydro-TTX is a highly specific blocker of the Na_v1.6 voltage-dependent sodium channel
Am J Physiol Cell Physiol 293: C783-C789, 2007. First published May 23, 2007; doi:10.1152/ajpcell.00070.2007 [Abstract] [Full Text] [PDF] [Supplemental Tables]

VASCULAR BIOLOGY:

Wasana K. Sumanasekera, Gamini U. Sumanasekera, Kathleen A. Mattingly, Susan M. Dougherty, Robert S. Keynton, and Carolyn M. Klinge: Estradiol and dihydrotestosterone regulate endothelial cell barrier function after hypergravity-induced alterations in MAPK activity
Am J Physiol Cell Physiol 293: C566-C573, 2007. First published March 14, 2007; doi:10.1152/ajpcell.00418.2006 [Abstract] [Full Text] [PDF]

Marina Puig-de-Morales-Marinkovic, Kevin T. Turner, James P. Butler, Jeffrey J. Fredberg, and Subra Suresh: Viscoelasticity of the human red blood cell
Am J Physiol Cell Physiol 293: C597-C605, 2007. First published April 11, 2007; doi:10.1152/ajpcell.00562.2006 [Abstract] [Full Text] [PDF]

Fanyin Meng, Roger Henson, and Tushar Patel: Chemotherapeutic stress selectively activates NF- ${kappa}$ B-dependent AKT and VEGF expression in liver cancer-derived endothelial cells
Am J Physiol Cell Physiol 293: C749-C760, 2007. First published May 30, 2007; doi:10.1152/ajpcell.00537.2006 [Abstract] [Full Text] [PDF]

Sebastian Albinsson and Per Hellstrand: Integration of signal pathways for stretch-dependent growth and differentiation in vascular smooth muscle
Am J Physiol Cell Physiol 293: C772-C782, 2007. First published May 16, 2007; doi:10.1152/ajpcell.00622.2006 [Abstract] [Full Text] [PDF]

D. K. Bowles, K. K. Maddali, V. C. Dhulipala, and D. H. Korzick: PKC ${delta}$ mediates anti-proliferative, pro-apoptic effects of testosterone on coronary smooth muscle
Am J Physiol Cell Physiol 293: C805-C813, 2007. First published May 16, 2007; doi:10.1152/ajpcell.00127.2007 [Abstract] [Full Text] [PDF]

GROWTH, DIFFERENTIATION, AND APOPTOSIS:

Masato Isome, Mark J. Lortie, Yasuko Murakami, Eva Parisi, Senya Matsufuji, and Joseph Satriano: The antiproliferative effects of agmatine correlate with the rate of cellular proliferation
Am J Physiol Cell Physiol 293: C705-C711, 2007. First published May 2, 2007; doi:10.1152/ajpcell.00084.2007 [Abstract] [Full Text] [PDF]

Virginie Mieulet, Mila Roceri, Catherine Espeillac, Athanassia Sotiropoulos, Mickael Ohanna, Viola Oorschot, Judith Klumperman, Marco Sandri, and Mario Pende: S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover
Am J Physiol Cell Physiol 293: C712-C722, 2007. First published May 9, 2007; doi:10.1152/ajpcell.00499.2006 [Abstract] [Full Text] [PDF]

PROTEIN AND VESICLE TRAFFICKING, CYTOSKELETON:

Srirangapatnam G. Venkatesh, Jinlian Tan, Sven-Ulrik Gorr, and Douglas S. Darling: Isoproterenol increases sorting of parotid gland cargo proteins to the basolateral pathway
Am J Physiol Cell Physiol 293: C558-C565, 2007. First published May 30, 2007; doi:10.1152/ajpcell.00081.2007 [Abstract] [Full Text] [PDF]

CELLULAR METABOLISM:

Yuri Y. Sautin, Takahiko Nakagawa, Sergey Zharikov, and Richard J. Johnson: Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress
Am J Physiol Cell Physiol 293: C584-C596, 2007. First published April 11, 2007; doi:10.1152/ajpcell.00600.2006 [Abstract] [Full Text] [PDF] [Supplemental Figures]

Amit Agrawal, Asha Guttapalli, Srinivas Narayan, Todd J. Albert, Irving M. Shapiro, and Makarand V. Risbud: Normoxic stabilization of HIF-1 ${alpha}$ drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral disk
Am J Physiol Cell Physiol 293: C621-C631, 2007. First published April 18, 2007; doi:10.1152/ajpcell.00538.2006 [Abstract] [Full Text] [PDF]

Hyoung Kyu Kim, Won Sun Park, Sung Hyun Kang, Mohamad Warda, Nari Kim, Jae-Hong Ko, Abd El-bary Prince, and Jin Han: Mitochondrial alterations in human gastric carcinoma cell line
Am J Physiol Cell Physiol 293: C761-C771, 2007. First published May 30, 2007; doi:10.1152/ajpcell.00043.2007 [Abstract] [Full Text] [PDF]

NERVOUS SYSTEM CELL BIOLOGY:

Barbara R. Grubb, Troy D. Rogers, Heather M. Kulaga, Kimberlie A. Burns, Robert L. Wonsetler, Randall R. Reed, and Lawrence E. Ostrowski: Olfactory epithelia exhibit progressive functional and morphological defects in CF mice
Am J Physiol Cell Physiol 293: C574-C583, 2007. First published April 11, 2007; doi:10.1152/ajpcell.00106.2007 [Abstract] [Full Text] [PDF] [Supplemental Tables]

Cover Caption:

Cover

Cover: Double-immunostaining of V-ATPase B1 knockout mouse epididymis showing aquaporin 9 (green) and V-ATPase B2 (red). Nuclei are stained with DAPI (blue). From: Da Silva N, Shum WWC, El-Annan J, Paunescu TG, McKee M, Smith PJS, Brown D, and Breton S. "Relocalization of the V-ATPase B2 subunit to the apical membrane of epididymal clear cells of mice deficient in the B1 subunit." Am J Physiol Cell Physiol 293: C199-C210, 2007.