EDITORIAL FOCUS:

M. A. Gray

Primary cilia and regulation of renal Na⁺ transport. Focus on "Heightened epithelial Na⁺ channel-mediated Na⁺ absorption in a murine polycystic kidney disease model epithelium lacking apical monocilia"
Am J Physiol Cell Physiol 290: C947-C949, 2006; doi:10.1152/ajpcell.00640.2005 [Full Text] [PDF]  

Christopher G. Sobey and Alyson A. Miller

Radicals spark interest in cerebral vasodilator mechanisms. Focus on "TNF- dilates cerebral arteries via NAD(P)H oxidase-dependent Ca²⁺ spark activation"
Am J Physiol Cell Physiol 290: C950-C951, 2006; doi:10.1152/ajpcell.00601.2005 [Full Text] [PDF]  

MEMBRANE TRANSPORTERS, ION CHANNELS, AND PUMPS:

Dragos Olteanu, Bradley K. Yoder, Wen Liu, Mandy J. Croyle, Elisabeth A. Welty, Kelley Rosborough, J. Michael Wyss, P. Darwin Bell, Lisa M. Guay-Woodford, Mark O. Bevensee, Lisa M. Satlin, and Erik M. Schwiebert

Heightened epithelial Na⁺ channel-mediated Na⁺ absorption in a murine polycystic kidney disease model epithelium lacking apical monocilia
Am J Physiol Cell Physiol 290: C952-C963, 2006. First published October 5, 2005; doi:10.1152/ajpcell.00339.2005 [Abstract] [Full Text] [PDF]  

Moon Young Kim, Guo Hua Liang, Ji Aee Kim, Young Ju Kim, Seikwan Oh, and Suk Hyo Suh

Sphingosine-1-phosphate activates BK_Ca channels independently of G protein-coupled receptor in human endothelial cells
Am J Physiol Cell Physiol 290: C1000-C1008, 2006. First published November 2, 2005; doi:10.1152/ajpcell.00353.2005 [Abstract] [Full Text] [PDF]  

Min Tae Kim, Byung Joo Kim, Jae Hwa Lee, Seong Chun Kwon, Dong Soo Yeon, Dong Ki Yang, Insuk So, and Ki Whan Kim

Involvement of calmodulin and myosin light chain kinase in activation of mTRPC5 expressed in HEK cells
Am J Physiol Cell Physiol 290: C1031-C1040, 2006. First published November 23, 2005; doi:10.1152/ajpcell.00602.2004 [Abstract] [Full Text] [PDF]  

Jerod Denton, Keith Nehrke, Xiaoyan Yin, Andrew M. Beld, and Kevin Strange

Altered gating and regulation of a carboxy-terminal ClC channel mutant expressed in the Caenorhabditis elegans oocyte
Am J Physiol Cell Physiol 290: C1109-C1118, 2006. First published November 23, 2005; doi:10.1152/ajpcell.00423.2005 [Abstract] [Full Text] [PDF]  

Oscar A. Candia, Lawrence J. Alvarez, and Aldo C. Zamudio

Regulation of water permeability in rabbit conjunctival epithelium by anisotonic conditions
Am J Physiol Cell Physiol 290: C1168-C1178, 2006; doi:10.1152/ajpcell.00254.2005 [Abstract] [Full Text] [PDF]  

Kenneth J. Cavanaugh, Taylor S. Cohen, and Susan S. Margulies

Stretch increases alveolar epithelial permeability to uncharged micromolecules
Am J Physiol Cell Physiol 290: C1179-C1188, 2006. First published November 9, 2005; doi:10.1152/ajpcell.00355.2004 [Abstract] [Full Text] [PDF]  

Melissa L. Palmer, So Yeong Lee, Peter J. Maniak, Dan Carlson, Scott C. Fahrenkrug, and Scott M. O'Grady

Protease-activated receptor regulation of Cl^– secretion in Calu-3 cells requires prostaglandin release and CFTR activation
Am J Physiol Cell Physiol 290: C1189-C1198, 2006; doi:10.1152/ajpcell.00464.2005 [Abstract] [Full Text] [PDF]  

Chung-Jiuan Jeng, Yu-Ting Chen, Yi-Wen Chen, and Chih-Yung Tang

Dominant-negative effects of human P/Q-type Ca²⁺ channel mutations associated with episodic ataxia type 2
Am J Physiol Cell Physiol 290: C1209-C1220, 2006. First published November 23, 2005; doi:10.1152/ajpcell.00247.2005 [Abstract] [Full Text] [PDF]  

Le Chen, Xi-Yuan Lu, Jun Li, Ji-Dong Fu, Zhao-Nian Zhou, and Huang-Tian Yang

Intermittent hypoxia protects cardiomyocytes against ischemia-reperfusion injury-induced alterations in Ca²⁺ homeostasis and contraction via the sarcoplasmic reticulum and Na⁺/Ca²⁺ exchange mechanisms
Am J Physiol Cell Physiol 290: C1221-C1229, 2006. First published November 23, 2005; doi:10.1152/ajpcell.00526.2005 [Abstract] [Full Text] [PDF]  

Morgan D. Fullerton, Laura Wagner, Zongfei Yuan, and Marica Bakovic

Impaired trafficking of choline transporter-like protein-1 at plasma membrane and inhibition of choline transport in THP-1 monocyte-derived macrophages
Am J Physiol Cell Physiol 290: C1230-C1238, 2006. First published November 30, 2005; doi:10.1152/ajpcell.00255.2005 [Abstract] [Full Text] [PDF]  

MUSCLE CELL BIOLOGY AND CELL MOTILITY:

X. D. Wang, F. Kawano, Y. Matsuoka, K. Fukunaga, M. Terada, M. Sudoh, A. Ishihara, and Y. Ohira

Mechanical load-dependent regulation of satellite cell and fiber size in rat soleus muscle
Am J Physiol Cell Physiol 290: C981-C989, 2006. First published November 16, 2005; doi:10.1152/ajpcell.00298.2005 [Abstract] [Full Text] [PDF]  

E. P. Debold, J. Romatowski, and R. H. Fitts

The depressive effect of P_i on the force-pCa relationship in skinned single muscle fibers is temperature dependent
Am J Physiol Cell Physiol 290: C1041-C1050, 2006. First published November 9, 2005; doi:10.1152/ajpcell.00342.2005 [Abstract] [Full Text] [PDF]  

Elen H. Miyabara, Jody L. Martin, Tina M. Griffin, Anselmo S. Moriscot, and Ruben Mestril

Overexpression of inducible 70-kDa heat shock protein in mouse attenuates skeletal muscle damage induced by cryolesioning
Am J Physiol Cell Physiol 290: C1128-C1138, 2006. First published November 16, 2005; doi:10.1152/ajpcell.00399.2005 [Abstract] [Full Text] [PDF]  

Esther Verburg, Travis L. Dutka, and Graham D. Lamb

Long-lasting muscle fatigue: partial disruption of excitation-contraction coupling by elevated cytosolic Ca²⁺ concentration during contractions
Am J Physiol Cell Physiol 290: C1199-C1208, 2006. First published November 23, 2005; doi:10.1152/ajpcell.00469.2005 [Abstract] [Full Text] [PDF]  

Alice-Corina Ceacareanu, Bogdan Ceacareanu, Daming Zhuang, Yingzi Chang, Ramesh M. Ray, Leena Desai, Kenneth E. Chapman, Christopher M. Waters, and Aviv Hassid

Nitric oxide attenuates IGF-I-induced aortic smooth muscle cell motility by decreasing Rac1 activity: essential role of PTP-PEST and p130^cas
Am J Physiol Cell Physiol 290: C1263-C1270, 2006. First published December 14, 2005; doi:10.1152/ajpcell.00241.2005 [Abstract] [Full Text] [PDF]  

RECEPTORS AND SIGNAL TRANSDUCTION:

Luiz Artur Poletto Chaves, Endrigo Piva Pontelli, and Wamberto Antonio Varanda

P2X receptors in mouse Leydig cells
Am J Physiol Cell Physiol 290: C1009-C1017, 2006. First published November 16, 2005; doi:10.1152/ajpcell.00506.2005 [Abstract] [Full Text] [PDF]  

Yun Tao, Kenneth A. Drabik, Tonya S. Waypa, Mark W. Musch, John C. Alverdy, Olaf Schneewind, Eugene B. Chang, and Elaine O. Petrof

Soluble factors from Lactobacillus GG activate MAPKs and induce cytoprotective heat shock proteins in intestinal epithelial cells
Am J Physiol Cell Physiol 290: C1018-C1030, 2006. First published November 23, 2005; doi:10.1152/ajpcell.00131.2005 [Abstract] [Full Text] [PDF]  

Yu Chen, Naoyuki Hashiguchi, Linda Yip, and Wolfgang G. Junger

Hypertonic saline enhances neutrophil elastase release through activation of P2 and A3 receptors
Am J Physiol Cell Physiol 290: C1051-C1059, 2006. First published November 9, 2005; doi:10.1152/ajpcell.00216.2005 [Abstract] [Full Text] [PDF]  

Ying Tian, Sheri E. Kelemen, and Michael V. Autieri

Inhibition of AIF-1 expression by constitutive siRNA expression reduces macrophage migration, proliferation, and signal transduction initiated by atherogenic stimuli
Am J Physiol Cell Physiol 290: C1083-C1091, 2006. First published November 16, 2005; doi:10.1152/ajpcell.00381.2005 [Abstract] [Full Text] [PDF]  

Hiroyoshi Aoki, Hirohide Ohnishi, Kouji Hama, Takako Ishijima, Yukihiro Satoh, Kazunobu Hanatsuka, Akira Ohashi, Shinichi Wada, Tomohiko Miyata, Hiroto Kita, Hironori Yamamoto, Hiroyuki Osawa, Kiichi Sato, Kiichi Tamada, Hiroshi Yasuda, Hirosato Mashima, and Kentaro Sugano

Autocrine loop between TGF-₁ and IL-1 through Smad3- and ERK-dependent pathways in rat pancreatic stellate cells
Am J Physiol Cell Physiol 290: C1100-C1108, 2006. First published December 21, 2005; doi:10.1152/ajpcell.00465.2005 [Abstract] [Full Text] [PDF]  

Wenyi Zhang, Iwona Hirschler-Laszkiewicz, Qin Tong, Kathleen Conrad, Shao-Cong Sun, Linda Penn, Dwayne L. Barber, Richard Stahl, David J. Carey, Joseph Y. Cheung, and Barbara A. Miller

TRPM2 is an ion channel that modulates hematopoietic cell death through activation of caspases and PARP cleavage
Am J Physiol Cell Physiol 290: C1146-C1159, 2006. First published November 23, 2005; doi:10.1152/ajpcell.00205.2005 [Abstract] [Full Text] [PDF]  

Li Liu, Yukisato Ishida, Gbolahan Okunade, Gary E. Shull, and Richard J. Paul

Role of plasma membrane Ca²⁺-ATPase in contraction-relaxation processes of the bladder: evidence from PMCA gene-ablated mice
Am J Physiol Cell Physiol 290: C1239-C1247, 2006. First published November 16, 2005; doi:10.1152/ajpcell.00440.2005 [Abstract] [Full Text] [PDF]  

VASCULAR BIOLOGY:

Sergey Y. Cheranov and Jonathan H. Jaggar

TNF- dilates cerebral arteries via NAD(P)H oxidase-dependent Ca²⁺ spark activation
Am J Physiol Cell Physiol 290: C964-C971, 2006. First published November 2, 2005; doi:10.1152/ajpcell.00499.2005 [Abstract] [Full Text] [PDF]  

Jun-Tzu Chao, Luis A. Martinez-Lemus, Stephen J. Kaufman, Gerald A. Meininger, Kenneth S. Ramos, and Emily Wilson

Modulation of ₇-integrin-mediated adhesion and expression by platelet-derived growth factor in vascular smooth muscle cells
Am J Physiol Cell Physiol 290: C972-C980, 2006. First published November 9, 2005; doi:10.1152/ajpcell.00136.2005 [Abstract] [Full Text] [PDF]  

Hadil Abuarqoub, Roberta Foresti, Colin J. Green, and Roberto Motterlini

Heme oxygenase-1 mediates the anti-inflammatory actions of 2'-hydroxychalcone in RAW 264.7 murine macrophages
Am J Physiol Cell Physiol 290: C1092-C1099, 2006. First published November 16, 2005; doi:10.1152/ajpcell.00380.2005 [Abstract] [Full Text] [PDF]  

GROWTH, DIFFERENTIATION, AND APOPTOSIS:

Ho Jae Han, Jung Sun Heo, and Yun Jung Lee

Estradiol-17 stimulates proliferation of mouse embryonic stem cells: involvement of MAPKs and CDKs as well as protooncogenes
Am J Physiol Cell Physiol 290: C1067-C1075, 2006. First published November 16, 2005; doi:10.1152/ajpcell.00222.2005 [Abstract] [Full Text] [PDF]  

Preeti Malladi, Yue Xu, Michael Chiou, Amato J. Giaccia, and Michael T. Longaker

Effect of reduced oxygen tension on chondrogenesis and osteogenesis in adipose-derived mesenchymal cells
Am J Physiol Cell Physiol 290: C1139-C1146, 2006. First published November 16, 2005; doi:10.1152/ajpcell.00415.2005 [Abstract] [Full Text] [PDF]  

PROTEIN AND VESICLE TRAFFICKING, CYTOSKELETON:

Shiguang Liu, Donna B. Stolz, Penny L. Sappington, Carlos A. Macias, Meaghan E. Killeen, Jyrki J. Tenhunen, Russell L. Delude, and Mitchell P. Fink

HMGB1 is secreted by immunostimulated enterocytes and contributes to cytomix-induced hyperpermeability of Caco-2 monolayers
Am J Physiol Cell Physiol 290: C990-C999, 2006. First published November 9, 2005; doi:10.1152/ajpcell.00308.2005 [Abstract] [Full Text] [PDF]  

Gary Hin-Fai Yam, Nils Bosshard, Christian Zuber, Beat Steinmann, and Jürgen Roth

Pharmacological chaperone corrects lysosomal storage in Fabry disease caused by trafficking-incompetent variants
Am J Physiol Cell Physiol 290: C1076-C1082, 2006; doi:10.1152/ajpcell.00426.2005 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]  

Simonetta Lisi, Roberta Botta, Aldo Pinchera, A. Bernard Collins, Samuel Refetoff, Peter Arvan, Guojun Bu, Lucia Grasso, Vladimir Marshansky, Shaliha Bechoua, Andres Hurtado-Lorenzo, Claudio Marcocci, Dennis Brown, Robert T. McCluskey, and Michele Marinò

Defective thyroglobulin storage in LDL receptor-associated protein-deficient mice
Am J Physiol Cell Physiol 290: C1160-C1167, 2006. First published November 23, 2005; doi:10.1152/ajpcell.00382.2005 [Abstract] [Full Text] [PDF]  

EXTRACELLULAR MATRIX, CELL INTERACTIONS:

Zhongyong Li, Zhiyi Zhou, Marnie M. Saunders, and Henry J. Donahue

Modulation of connexin43 alters expression of osteoblastic differentiation markers
Am J Physiol Cell Physiol 290: C1248-C1255, 2006. First published November 30, 2005; doi:10.1152/ajpcell.00428.2005 [Abstract] [Full Text] [PDF]  

Emeline F. Nandrot, Monika Anand, Mousumi Sircar, and Silvia C. Finnemann

Novel role for _v5-integrin in retinal adhesion and its diurnal peak
Am J Physiol Cell Physiol 290: C1256-C1262, 2006. First published December 7, 2005; doi:10.1152/ajpcell.00480.2005 [Abstract] [Full Text] [PDF]  

CELLULAR METABOLISM:

C. S. Kraft, C. M. R. LeMoine, C. N. Lyons, D. Michaud, C. R. Mueller, and C. D. Moyes

Control of mitochondrial biogenesis during myogenesis
Am J Physiol Cell Physiol 290: C1119-C1127, 2006; doi:10.1152/ajpcell.00463.2005 [Abstract] [Full Text] [PDF]  

NERVOUS SYSTEM CELL BIOLOGY:

So-Young Lee, Bo-Hwa Choi, Eun-Mi Hur, Jong-Hee Lee, Sung-Jin Lee, Chin Ok Lee, and Kyong-Tai Kim

Norepinephrine activates store-operated Ca²⁺ entry coupled to large-conductance Ca²⁺-activated K⁺ channels in rat pinealocytes
Am J Physiol Cell Physiol 290: C1060-C1066, 2006. First published November 9, 2005; doi:10.1152/ajpcell.00343.2005 [Abstract] [Full Text] [PDF]  

LETTERS TO THE EDITOR:

Mark C. P. Haigney, Shao-kui Wei, Dan H. Schulze, Abdul M. Ruknudin, and Satoshi Matsuoka

Response to "-adrenergic stimulation does not activate Na⁺/Ca²⁺ exchange current in guinea pig, mouse, and rat ventricular myocytes"
Am J Physiol Cell Physiol 290: C1271-C1271, 2006; doi:10.1152/ajpcell.00541.2005 [Full Text] [PDF]  

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