AJP - Cell Physiology -- Table of Contents (June 1 2005, 288 [6])

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EDITORIAL FOCUS:

Karl S. Matlin: Clues to occludin. Focus on "Knockdown of occludin expression leads to diverse phenotypic alterations in epithelial cells"
Am J Physiol Cell Physiol 288: C1191-C1192, 2005; doi:10.1152/ajpcell.00067.2005 [Full Text] [PDF]

TRANSLATIONAL PHYSIOLOGY:

Roman Ginnan and Harold A. Singer: PKC- ${delta}$ -dependent pathways contribute to PDGF-stimulated ERK1/2 activation in vascular smooth muscle
Am J Physiol Cell Physiol 288: C1193-C1201, 2005. First published January 26, 2005; doi:10.1152/ajpcell.00499.2004 [Abstract] [Full Text] [PDF]

MEMBRANE TRANSPORTERS, ION CHANNELS, AND PUMPS:

Takashi Murayama, Toshiharu Oba, Shigeki Kobayashi, Noriaki Ikemoto, and Yasuo Ogawa: Postulated role of interdomain interactions within the type 1 ryanodine receptor in the low gain of Ca²⁺-induced Ca²⁺ release activity of mammalian skeletal muscle sarcoplasmic reticulum
Am J Physiol Cell Physiol 288: C1222-C1230, 2005. First published January 26, 2005; doi:10.1152/ajpcell.00415.2004 [Abstract] [Full Text] [PDF]

Alan S. L. Yu, Karin M. McCarthy, Stacy A. Francis, Joanne M. McCormack, Jean Lai, Rick A. Rogers, Robert D. Lynch, and Eveline E. Schneeberger: Knockdown of occludin expression leads to diverse phenotypic alterations in epithelial cells
Am J Physiol Cell Physiol 288: C1231-C1241, 2005. First published February 2, 2005; doi:10.1152/ajpcell.00581.2004 [Abstract] [Full Text] [PDF]

Georgi V. Petkov and Mark T. Nelson: Differential regulation of Ca²⁺-activated K⁺ channels by ${beta}$ -adrenoceptors in guinea pig urinary bladder smooth muscle
Am J Physiol Cell Physiol 288: C1255-C1263, 2005. First published January 26, 2005; doi:10.1152/ajpcell.00381.2004 [Abstract] [Full Text] [PDF]

Juan Codina, Jian Li, and Thomas D. DuBose, Jr.: CD63 interacts with the carboxy terminus of the colonic H⁺-K⁺-ATPase to increase plasma membrane localization and ⁸⁶Rb⁺ uptake
Am J Physiol Cell Physiol 288: C1279-C1286, 2005. First published January 12, 2005; doi:10.1152/ajpcell.00463.2004 [Abstract] [Full Text] [PDF]

Ying-Hong Feng, Liqin Wang, Qifang Wang, Xin Li, Robin Zeng, and George I. Gorodeski: ATP stimulates GRK-3 phosphorylation and ${beta}$ -arrestin-2-dependent internalization of P2X₇ receptor
Am J Physiol Cell Physiol 288: C1342-C1356, 2005. First published February 23, 2005; doi:10.1152/ajpcell.00315.2004 [Abstract] [Full Text] [PDF]

Luis Beaugé and Reinaldo DiPolo: SEA-0400, a potent inhibitor of the Na⁺/Ca²⁺ exchanger, as a tool to study exchanger ionic and metabolic regulation
Am J Physiol Cell Physiol 288: C1374-C1380, 2005. First published February 9, 2005; doi:10.1152/ajpcell.00492.2004 [Abstract] [Full Text] [PDF]

Camillo Peracchia and Lillian L. Peracchia: Inversion of both gating polarity and CO₂ sensitivity of voltage gating with D3N mutation of Cx50
Am J Physiol Cell Physiol 288: C1381-C1389, 2005. First published January 26, 2005; doi:10.1152/ajpcell.00348.2004 [Abstract] [Full Text] [PDF]

Hiroyuki Hamada, Hiroshi Ishiguro, Akiko Yamamoto, Sachiko Shimano-Futakuchi, Shigeru B. H. Ko, Toshiyuki Yoshikawa, Hidemi Goto, Motoji Kitagawa, Tetsuo Hayakawa, Yoshiteru Seo, and Satoru Naruse: Dual effects of n-alcohols on fluid secretion from guinea pig pancreatic ducts
Am J Physiol Cell Physiol 288: C1431-C1439, 2005. First published January 19, 2005; doi:10.1152/ajpcell.00373.2004 [Abstract] [Full Text] [PDF]

Nola Jean Ernest, Amy K. Weaver, Lauren B. Van Duyn, and Harald W. Sontheimer: Relative contribution of chloride channels and transporters to regulatory volume decrease in human glioma cells
Am J Physiol Cell Physiol 288: C1451-C1460, 2005. First published January 19, 2005; doi:10.1152/ajpcell.00503.2004 [Abstract] [Full Text] [PDF]

MUSCLE CELL BIOLOGY AND CELL MOTILITY:

Minkyung Kim, Sang Yun Cho, In Soo Han, Sang Don Koh, and Brian A. Perrino: CaM kinase II and phospholamban contribute to caffeine-induced relaxation of murine gastric fundus smooth muscle
Am J Physiol Cell Physiol 288: C1202-C1210, 2005. First published January 19, 2005; doi:10.1152/ajpcell.00299.2004 [Abstract] [Full Text] [PDF]

Chad R. Hancock, Edwin Janssen, and Ronald L. Terjung: Skeletal muscle contractile performance and ADP accumulation in adenylate kinase-deficient mice
Am J Physiol Cell Physiol 288: C1287-C1297, 2005. First published January 19, 2005; doi:10.1152/ajpcell.00567.2004 [Abstract] [Full Text] [PDF]

Chad R. Hancock, Jeffrey J. Brault, Robert W. Wiseman, Ronald L. Terjung, and Ronald A. Meyer: ³¹P-NMR observation of free ADP during fatiguing, repetitive contractions of murine skeletal muscle lacking AK1
Am J Physiol Cell Physiol 288: C1298-C1304, 2005. First published February 2, 2005; doi:10.1152/ajpcell.00621.2004 [Abstract] [Full Text] [PDF]

Daniela Danieli-Betto, Elena Germinario, Alessandra Esposito, Aram Megighian, Menotti Midrio, Barbara Ravara, Ernesto Damiani, Luciano Dalla Libera, Roger A. Sabbadini, and Romeo Betto: Sphingosine 1-phosphate protects mouse extensor digitorum longus skeletal muscle during fatigue
Am J Physiol Cell Physiol 288: C1367-C1373, 2005. First published January 19, 2005; doi:10.1152/ajpcell.00246.2004 [Abstract] [Full Text] [PDF]

RECEPTORS AND SIGNAL TRANSDUCTION:

Weidong Geng, Zenglu Wang, Jianning Zhang, Berenice Y. Reed, Charles Y. C. Pak, and Orson W. Moe: Cloning and characterization of the human soluble adenylyl cyclase
Am J Physiol Cell Physiol 288: C1305-C1316, 2005. First published January 19, 2005; doi:10.1152/ajpcell.00584.2004 [Abstract] [Full Text] [PDF]

Franco Capozza, Terry P. Combs, Alex W. Cohen, You-Ree Cho, So-Young Park, William Schubert, Terence M. Williams, Dawn L. Brasaemle, Linda A. Jelicks, Philipp E. Scherer, Jason K. Kim, and Michael P. Lisanti: Caveolin-3 knockout mice show increased adiposity and whole body insulin resistance, with ligand-induced insulin receptor instability in skeletal muscle
Am J Physiol Cell Physiol 288: C1317-C1331, 2005. First published February 2, 2005; doi:10.1152/ajpcell.00489.2004 [Abstract] [Full Text] [PDF]

Chih-Ko Yeh, Paramita M. Ghosh, Howard Dang, Qun Liu, Alan L. Lin, Bin-Xian Zhang, and Michael S. Katz: ${beta}$ -Adrenergic-responsive activation of extracellular signal-regulated protein kinases in salivary cells: role of epidermal growth factor receptor and cAMP
Am J Physiol Cell Physiol 288: C1357-C1366, 2005. First published February 2, 2005; doi:10.1152/ajpcell.00370.2004 [Abstract] [Full Text] [PDF]

Richard Bouley, Herbert Y. Lin, Malay K. Raychowdhury, Vladimir Marshansky, Dennis Brown, and Dennis A. Ausiello: Downregulation of the vasopressin type 2 receptor after vasopressin-induced internalization: involvement of a lysosomal degradation pathway
Am J Physiol Cell Physiol 288: C1390-C1401, 2005. First published January 26, 2005; doi:10.1152/ajpcell.00353.2004 [Abstract] [Full Text] [PDF]

Gloria Bonuccelli, Federica Sotgia, Philippe G. Frank, Terence M. Williams, Cecilia J. de Almeida, Herbert B. Tanowitz, Philipp E. Scherer, Kylie A. Hotchkiss, Bruce I. Terman, Brent Rollman, Abdelkrim Alileche, Jürgen Brojatsch, and Michael P. Lisanti: ATR/TEM8 is highly expressed in epithelial cells lining Bacillus anthracis’ three sites of entry: implications for the pathogenesis of anthrax infection
Am J Physiol Cell Physiol 288: C1402-C1410, 2005. First published February 2, 2005; doi:10.1152/ajpcell.00582.2004 [Abstract] [Full Text] [PDF]

GROWTH, DIFFERENTIATION, AND APOPTOSIS:

Steven J. Pardo, Mamta J. Patel, Michelle C. Sykes, Manu O. Platt, Nolan L. Boyd, George P. Sorescu, Min Xu, Jack J. W. A. van Loon, May D. Wang, and Hanjoong Jo: Simulated microgravity using the Random Positioning Machine inhibits differentiation and alters gene expression profiles of 2T3 preosteoblasts
Am J Physiol Cell Physiol 288: C1211-C1221, 2005. First published February 2, 2005; doi:10.1152/ajpcell.00222.2004 [Abstract] [Full Text] [PDF]

PROTEIN AND VESICLE TRAFFICKING, CYTOSKELETON:

Lixin Zhu, Yuechueng Liu, and John G. Forte: Ezrin oligomers are the membrane-bound dormant form in gastric parietal cells
Am J Physiol Cell Physiol 288: C1242-C1254, 2005. First published March 23, 2005; doi:10.1152/ajpcell.00521.2004 [Abstract] [Full Text] [PDF]

Xiaorui Shi, Peter G. Gillespie, and Alfred L. Nuttall: Na⁺ influx triggers bleb formation on inner hair cells
Am J Physiol Cell Physiol 288: C1332-C1341, 2005. First published February 2, 2005; doi:10.1152/ajpcell.00522.2004 [Abstract] [Full Text] [PDF] [Supplemental movies]

Bo Wang, Fiona G. Wylie, Rohan D. Teasdale, and Jennifer L. Stow: Polarized trafficking of E-cadherin is regulated by Rac1 and Cdc42 in Madin-Darby canine kidney cells
Am J Physiol Cell Physiol 288: C1411-C1419, 2005. First published February 2, 2005; doi:10.1152/ajpcell.00533.2004 [Abstract] [Full Text] [PDF]

Silvia Chifflet, Julio A. Hernández, and Silvina Grasso: A possible role for membrane depolarization in epithelial wound healing
Am J Physiol Cell Physiol 288: C1420-C1430, 2005; doi:10.1152/ajpcell.00259.2004 [Abstract] [Full Text] [PDF]

CELLULAR METABOLISM:

Cèlia García-Martínez, Mario Marotta, Rodrigo Moore-Carrasco, Maria Guitart, Marta Camps, Silvia Busquets, Eulàlia Montell, and Anna M. Gómez-Foix: Impact on fatty acid metabolism and differential localization of FATP1 and FAT/CD36 proteins delivered in cultured human muscle cells
Am J Physiol Cell Physiol 288: C1264-C1272, 2005; doi:10.1152/ajpcell.00271.2004 [Abstract] [Full Text] [PDF]

Werner J. H. Koopman, Sjoerd Verkaart, Henk-Jan Visch, Francois H. van der Westhuizen, Michael P. Murphy, Lambertus W. P. J. van den Heuvel, Jan A. M. Smeitink, and Peter H. G. M. Willems: Inhibition of complex I of the electron transport chain causes O₂^–·-mediated mitochondrial outgrowth
Am J Physiol Cell Physiol 288: C1440-C1450, 2005. First published January 12, 2005; doi:10.1152/ajpcell.00607.2004 [Abstract] [Full Text] [PDF]

METHODS IN CELL PHYSIOLOGY:

Jae-Kyun Ko and Jianjie Ma: A rapid and efficient PCR-based mutagenesis method applicable to cell physiology study
Am J Physiol Cell Physiol 288: C1273-C1278, 2005. First published January 19, 2005; doi:10.1152/ajpcell.00517.2004 [Abstract] [Full Text] [PDF]

CORRIGENDA:

: CORRIGENDA
Am J Physiol Cell Physiol 288: C1461-C1461, 2005; doi:10.1152/ajpcell.00122.2005 [Full Text] [PDF]

Cover Caption:

Cover Cover: Gene delivery of low-molecular-weight caldesmon (l-CaD) protects cytoskeletal cell membrane integrity against adenoviral infection independently of myosin ATPase and actin assembly. Human l-CaD was expressed in avian fibroblast DF-1 cells, a spontaneously immortalized but nontransformed cell line null for l-CaD, using calcium phosphate coprecipitation at a multiplicity of infection of 200. Colocalization of human l-CaD with avian microfilaments was determined using immunofluorescence imaging. Cells were coimmunostained with a mouse IgG anti-l-CaD primary antibody, an Oregon Green-conjugated goat anti-mouse secondary antibody, and Texas red phalloidin to visualize l-CaD and microfilaments, respectively. Images were obtained using FITC and rhodamine filters at ×100 magnification. Images depicting l-CaDstained cells (green) and actin-stained cells (magenta) from the same field of view were then overlaid as shown to display colocalization (white- or lighter magenta-colored filaments). See related article by Haxhinasto K, Kamath A, Blackwell K, Bodmer J, Van Heukelom J, English A, Bai EW, and Moy AB. Am J Physiol Cell Physiol 287: C1125–C1138, 2004.