AJP - Cell Physiology -- Table of Contents (May 1 2003, 284 [5])

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EDITORIAL FOCUS:

Michael J. Caplan: How megalin finds its way: identification of a novel apical sorting motif. Focus on "Identification of an apical sorting determinant in the cytoplasmic tail of megalin"
Am J Physiol Cell Physiol 284: C1101-C1104, 2003; doi:10.1152/ajpcell.00004.2003 [Full Text] [PDF]

MEMBRANE TRANSPORTERS, ION CHANNELS, AND PUMPS:

Xing Cai Sun, Chang-Bin Zhai, Miao Cui, Yanqiu Chen, Lonny R. Levin, Jochen Buck, and Joseph A. Bonanno: HCO^-₃-dependent soluble adenylyl cyclase activates cystic fibrosis transmembrane conductance regulator in corneal endothelium
Am J Physiol Cell Physiol 284: C1114-C1122, 2003. First published January 8, 2003; doi:10.1152/ajpcell.00400.2002 [Abstract] [Full Text] [PDF]

Pertteli Salmenperä, Sammy Hämäläinen, Mika Hukkanen, and Esko Kankuri: Interferon- $gamma$ induces C/EBP $beta$ expression and activity through MEK/ERK and p38 in T84 colon epithelial cells
Am J Physiol Cell Physiol 284: C1133-C1139, 2003. First published December 27, 2002; doi:10.1152/ajpcell.00293.2002 [Abstract] [Full Text] [PDF]

Xiang Q. Gu and Gabriel G. Haddad: Maturation of neuronal excitability in hippocampal neurons of mice chronically exposed to cyclic hypoxia
Am J Physiol Cell Physiol 284: C1156-C1163, 2003; doi:10.1152/ajpcell.00432.2002 [Abstract] [Full Text] [PDF]

Ai-Yu Gong, Pamela S. Tietz, Melissa A. Muff, Patrick L. Splinter, Robert C. Huebert, Mathias Z. Strowski, Xian-Ming Chen, and Nicholas F. LaRusso: Somatostatin stimulates ductal bile absorption and inhibits ductal bile secretion in mice via SSTR2 on cholangiocytes
Am J Physiol Cell Physiol 284: C1205-C1214, 2003; doi:10.1152/ajpcell.00313.2002 [Abstract] [Full Text] [PDF]

Marina N. Chernova, Andrew K. Stewart, Lianwei Jiang, David J. Friedman, Yune Z. Kunes, and Seth L. Alper: Structure-function relationships of AE2 regulation by Ca²⁺_i-sensitive stimulators NH⁺₄ and hypertonicity
Am J Physiol Cell Physiol 284: C1235-C1246, 2003. First published January 15, 2003; doi:10.1152/ajpcell.00522.2002 [Abstract] [Full Text] [PDF]

Zhao Zhang, Yanfang Xu, Pei Hong Dong, Dipika Sharma, and Nipavan Chiamvimonvat: A negatively charged residue in the outer mouth of rat sodium channel determines the gating kinetics of the channel
Am J Physiol Cell Physiol 284: C1247-C1254, 2003. First published January 22, 2003; doi:10.1152/ajpcell.00471.2002 [Abstract] [Full Text] [PDF]

Hua Xu, Michael Inouye, Eric R. Hines, James F. Collins, and Fayez K. Ghishan: Transcriptional regulation of the human NaP_i-IIb cotransporter by EGF in Caco-2 cells involves c-myb
Am J Physiol Cell Physiol 284: C1262-C1271, 2003. First published January 15, 2003; doi:10.1152/ajpcell.00456.2002 [Abstract] [Full Text] [PDF]

Kenneth R. Hallows, Gary P. Kobinger, James M. Wilson, Lee A. Witters, and J. Kevin Foskett: Physiological modulation of CFTR activity by AMP-activated protein kinase in polarized T84 cells
Am J Physiol Cell Physiol 284: C1297-C1308, 2003. First published January 2, 2003; doi:10.1152/ajpcell.00227.2002 [Abstract] [Full Text] [PDF]

MUSCLE CELL BIOLOGY AND CELL MOTILITY:

S. E. Anderson, H. Liu, H. S. Ho, E. J. Lewis, and P. M. Cala: Age-related differences in Na⁺-dependent Ca²⁺ accumulation in rabbit hearts exposed to hypoxia and acidification
Am J Physiol Cell Physiol 284: C1123-C1132, 2003. First published January 8, 2003; doi:10.1152/ajpcell.00148.2002 [Abstract] [Full Text] [PDF]

Todd E. Gillis, Chris D. Moyes, and Glen F. Tibbits: Sequence mutations in teleost cardiac troponin C that are permissive of high Ca²⁺ affinity of site II
Am J Physiol Cell Physiol 284: C1176-C1184, 2003. First published January 8, 2003; doi:10.1152/ajpcell.00339.2002 [Abstract] [Full Text] [PDF]

RECEPTORS AND SIGNAL TRANSDUCTION:

Nathan K. Lebrasseur, Gregory M. Coté, Thomas A. Miller, Roger A. Fielding, and Douglas B. Sawyer: Regulation of neuregulin/ErbB signaling by contractile activity in skeletal muscle
Am J Physiol Cell Physiol 284: C1149-C1155, 2003. First published January 2, 2003; doi:10.1152/ajpcell.00487.2002 [Abstract] [Full Text] [PDF]

Chih-Ko Yeh, Tazuko K. Hymer, April L. Sousa, Bin-Xian Zhang, Meyer D. Lifschitz, and Michael S. Katz: Epidermal growth factor upregulates $beta$ -adrenergic receptor signaling in a human salivary cell line
Am J Physiol Cell Physiol 284: C1164-C1175, 2003. First published January 22, 2003; doi:10.1152/ajpcell.00343.2002 [Abstract] [Full Text] [PDF]

Michelle L. Seymour, Nosheen F. Zaidi, Morley D. Hollenberg, and Wallace K. MacNaughton: PAR₁-dependent and independent increases in COX-2 and PGE₂ in human colonic myofibroblasts stimulated by thrombin
Am J Physiol Cell Physiol 284: C1185-C1192, 2003. First published December 27, 2002; doi:10.1152/ajpcell.00126.2002 [Abstract] [Full Text] [PDF]

Scott F. Davis and Cindy L. Linn: Mechanism linking NMDA receptor activation to modulation of voltage-gated sodium current in distal retina
Am J Physiol Cell Physiol 284: C1193-C1204, 2003. First published January 29, 2003; doi:10.1152/ajpcell.00256.2002 [Abstract] [Full Text] [PDF]

Yukiko Kaneko, Tomohisa Ishikawa, Satoshi Amano, and Koichi Nakayama: Dual effect of nitric oxide on cytosolic Ca²⁺ concentration and insulin secretion in rat pancreatic $beta$ -cells
Am J Physiol Cell Physiol 284: C1215-C1222, 2003. First published January 15, 2003; doi:10.1152/ajpcell.00223.2002 [Abstract] [Full Text] [PDF]

Huiping Zhou and Karnam S. Murthy: Identification of the G protein-activating sequence of the single-transmembrane natriuretic peptide receptor C (NPR-C)
Am J Physiol Cell Physiol 284: C1255-C1261, 2003; doi:10.1152/ajpcell.00520.2002 [Abstract] [Full Text] [PDF]

A. P. Seale, N. H. Richman, III, T. Hirano, I. Cooke, and E. G. Grau: Cell volume increase and extracellular Ca²⁺ are needed for hyposmotically induced prolactin release in tilapia
Am J Physiol Cell Physiol 284: C1280-C1289, 2003. First published January 22, 2003; doi:10.1152/ajpcell.00531.2002 [Abstract] [Full Text] [PDF]

A. P. Seale, N. H. Richman, III, T. Hirano, I. Cooke, and E. G. Grau: Evidence that signal transduction for osmoreception is mediated by stretch-activated ion channels in tilapia
Am J Physiol Cell Physiol 284: C1290-C1296, 2003. First published January 22, 2003; doi:10.1152/ajpcell.00532.2002 [Abstract] [Full Text] [PDF]

GROWTH, DIFFERENTIATION, AND APOPTOSIS:

Richard Weller, Ann Schwentker, Timothy R. Billiar, and Yoram Vodovotz: Autologous nitric oxide protects mouse and human keratinocytes from ultraviolet B radiation-induced apoptosis
Am J Physiol Cell Physiol 284: C1140-C1148, 2003; doi:10.1152/ajpcell.00462.2002 [Abstract] [Full Text] [PDF]

PROTEIN AND VESICLE TRAFFICKING, CYTOSKELETON:

Tetsuro Takeda, Hajime Yamazaki, and Marilyn G. Farquhar: Identification of an apical sorting determinant in the cytoplasmic tail of megalin
Am J Physiol Cell Physiol 284: C1105-C1113, 2003. First published January 8, 2003; doi:10.1152/ajpcell.00514.2002 [Abstract] [Full Text] [PDF]

Marcel Tanudji, Sarah Hevi, and Steven L. Chuck: The nonclassic secretion of thioredoxin is not sensitive to redox state
Am J Physiol Cell Physiol 284: C1272-C1279, 2003. First published January 15, 2003; doi:10.1152/ajpcell.00521.2002 [Abstract] [Full Text] [PDF]

Dirk Roosterman, Fabien Schmidlin, and Nigel W. Bunnett: Rab5a and rab11a mediate agonist-induced trafficking of protease-activated receptor 2
Am J Physiol Cell Physiol 284: C1319-C1329, 2003. First published January 22, 2003; doi:10.1152/ajpcell.00540.2002 [Abstract] [Full Text] [PDF]

EXTRACELLULAR MATRIX, CELL INTERACTIONS:

Owen J. T. McCarty, Niven Tien, Bruce S. Bochner, and Konstantinos Konstantopoulos: Exogenous eosinophil activation converts PSGL-1-dependent binding to CD18-dependent stable adhesion to platelets in shear flow
Am J Physiol Cell Physiol 284: C1223-C1234, 2003. First published January 15, 2003; doi:10.1152/ajpcell.00403.2002 [Abstract] [Full Text] [PDF]

METHODS IN CELL PHYSIOLOGY:

K. J. Kelly, Ruben M. Sandoval, Kenneth W. Dunn, Bruce A. Molitoris, and Pierre C. Dagher: A novel method to determine specificity and sensitivity of the TUNEL reaction in the quantitation of apoptosis
Am J Physiol Cell Physiol 284: C1309-C1318, 2003. First published December 21, 2002; doi:10.1152/ajpcell.00353.2002 [Abstract] [Full Text] [PDF] [Supplemental Movies]

Cover Caption:

Cover

Cover: p73 overexpression causes apoptosis in vascular smooth muscle cells. p73/EGFP gene expression was controlled usinga tet-off system. Tet-off cells were maintained in doxycycline-containingmedium (bottom panels). Doxycycline was withdrawn for 5 days toinduce p73 expression (top panels), and the cells were stainedwith Hoechst 33258. Representative fields were examined undervisible light (right) and under illumination conditions appropriatefor Hoechst (middle) or green fluorescent protein (left) fluorophores.See related article by Davis BB, Dong Y, and Weiss RH. Am J PhysiolCell Physiol 284: C16-C23, 2003; 10.1152/ajpcell.00211.2002.