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Cover: p73 overexpression causes apoptosis in vascular smooth muscle cells. p73/EGFP gene expression was controlled using a tet-off system. Tet-off cells were maintained in doxycycline-containing medium (bottom panels). Doxycycline was withdrawn for 5 days to induce p73 expression (top panels), and the cells were stained with Hoechst 33258. Representative fields were examined under visible light (right) and under illumination conditions appropriate for Hoechst (middle) or green fluorescent protein (left) fluorophores. See related article by Davis BB, Dong Y, and Weiss RH. Am J Physiol Cell Physiol 284: C16-C23, 2003; 10.1152/ajpcell.00211.2002.
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