Volume 283, December 2002 Volume 52, December 2002

Pages C1646-C1654: De-An Wang, Haiming Du, Jonathan H. Jaggar, David N. Brindley, Gabor J. Tigyi, and Mitchell A. Watsky. "Injury-elicited differential transcriptional regulation of phospholipid growth factor receptors in the cornea." On page C1647 in MATERIALS AND METHODS, Real-time PCR, 44 corneas were reported wounded, where the actual number was 32. In addition, 10 corneas were reported as control, where the actual number was 12. These experiments were performed in duplicate for each data point, not in triplicate as originally stated. As a result of these changes, an asterisk denoting significance over the S1P₁ wounded endothelium group is incorrect and has been deleted from Fig. 2C (page C1650), which should appear as shown below. Finally, on page C1650 in RESULTS, Endothelium, the sentence "The abundance of S1P₁ transcripts decreased modestly but significantly during wound healing." should now read "The abundance of S1P₁ transcripts in the endothelium showed no significant changes during wound healing." These changes do not affect the conclusions of the article in any way.

View larger version (27K): [in this window] [in a new window]   Fig. 2.   Quantitative changes of corneal PLGF receptor and -actin mRNAs measured using real-time PCR analysis. Total RNA from each of control, wound-healing (72 h), and peri-wound cells was analyzed. Known copy numbers of rabbit S1P1, LPA1, LPA3 and -actin cDNA were used as standards for determining absolute copy numbers. Values are means ± SE of 2 determinations. Scale on left corresponds to S1P1 and LPA1 transcript numbers; scale on right corresponds to LPA3 and -actin transcript numbers. *P < 0.001 vs. control. P < 0.05 vs. control.