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Am J Physiol Cell Physiol 287: C1560-C1568, 2004; doi:10.1152/ajpcell.00221.2004
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Transforming growth factor-{beta}1 signaling contributes to development of smooth muscle cells from embryonic stem cells
Am J Physiol Cell Physiol Sinha et al. 287: C1560

Smooth Muscle Movie

Real time video of a focal area of the ES cell derived embryoid body exhibiting visible slow smooth muscle- like contraction (once every 5 – 10 seconds). This area of slow contraction stained positively for SMMHC, a highly specific marker for SMC (see manuscript, fig. 2C) confirming that the contraction was due to SMC aggregates rather than cardiac or skeletal muscle.

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