Am J Physiol Cell Physiol Watch the video to learn how APS reaches out to developing nations.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Cell Physiol 266: C143-C148, 1994;
0363-6143/94 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Beaune, B.
Right arrow Articles by Coudert, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Beaune, B.
Right arrow Articles by Coudert, J.

AJP - Cell Physiology, Vol 266, Issue 1 C143-C148, Copyright © 1994 by American Physiological Society

ARTICLES

Effects of orchiectomy on EDL muscle ultrastructure and energy-supplying enzymes in growing male guinea pigs

B. Beaune, N. Fellmann, F. Villie, M. Marcollet and J. Coudert
Laboratoire de Physiologie-Biologie du Sport, Faculte de Medecine, Universite d'Auvergne, Clermont-Ferrand, France.

To investigate the influence of androgens on muscle maturation during growth, guinea pigs were orchiectomized (CX) or sham operated (SO) at the end of weaning. Extensor digitorum longus (EDL) muscles were removed at weeks 4, 8, and 12 of postnatal development. According to their contractile and metabolic characteristics, four fiber types were distinguished, called I, IIa, IIbox, and IIbglyc. Muscle maturation consisted of a concomitant decrease in percentages of type IIa and IIbglyc fibers and increase in the percentage of IIbox fibers in both groups. At week 12, fiber distributions were not different between the two groups. Citrate synthase activity fell and phosphofructokinase and lactate dehydrogenase (LDH) activities rose from week 4 to week 12 and were the same in CX and SO. Muscular LDH subunits increased in SO and decreased in CX during this period. In conclusion, fiber type distribution and enzyme activities at puberty were not androgen dependent in guinea pig EDL muscle. Conversely, these hormones acted on LDH isozyme distribution through the enhancement of the most glycolytic LDH fractions.


This article has been cited by other articles:


Home page
 J. Physiol.Home page
M. L. Armstrong, A. K. Dua, and C. L. Murrant
Potassium initiates vasodilatation induced by a single skeletal muscle contraction in hamster cremaster muscle
J. Physiol., June 1, 2007; 581(2): 841 - 852.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online