Am J Physiol Cell Physiol Add DOIs to your references at manuscript stage!
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Cell Physiol 260: C1325-C1331, 1991;
0363-6143/91 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Essig, D. A.
Right arrow Articles by Trannel, T. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Essig, D. A.
Right arrow Articles by Trannel, T. J.

AJP - Cell Physiology, Vol 260, Issue 6 C1325-C1331, Copyright © 1991 by American Physiological Society

ARTICLES

Expression of embryonic myosin heavy chain mRNA in stretched adult chicken skeletal muscle

D. A. Essig, D. L. Devol, P. J. Bechtel and T. J. Trannel
Division of Exercise Molecular Biology, College of Kinesiology, University of Illinois, Chicago 60680.

Chronic stretch of the chicken fast-twitch patagialis muscle increases the rate of growth and percentage of fast-twitch oxidative fibers. We have analyzed the effects of stretch on the expression of two previously identified "embryonic" myosin heavy chain (MHC) mRNAs (p251 and p110). Both MHC mRNAs were expressed in the patagialis at their highest levels in the embryo and 1 wk after hatching. During posthatch development (7-52 wk), the p110 mRNA was expressed in only trace quantities while the p251 mRNA was not detectable. After 2 wk of stretch of the patagialis in 7- or 38-wk-old birds, the p110 mRNA was increased to levels similar to that found in patagialis of newly hatched chicks, whereas expression of the p251 transcript was not affected. The existence of two other MHC mRNAs homologous to the p110 mRNA was suggested by the S1 mapping analysis, one of which was expressed at dramatically reduced levels in the stretched patagialis. It is concluded that stretch can cause selective alterations in the expression of developmentally regulated MHC isoforms in chicken fast-twitch muscle.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
M. A. F. Singh, W. Ding, T. J. Manfredi, G. S. Solares, E. F. O'Neill, K. M. Clements, N. D. Ryan, J. J. Kehayias, R. A. Fielding, and W. J. Evans
Insulin-like growth factor I in skeletal muscle after weight-lifting exercise in frail elders
Am J Physiol Endocrinol Metab, July 1, 1999; 277(1): E135 - E143.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online