Am J Physiol Cell Physiol Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Cell Physiol 252: C450-C453, 1987;
0363-6143/87 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Underwood, L. E.
Right arrow Articles by Williams, R. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Underwood, L. E.
Right arrow Articles by Williams, R. S.

AJP - Cell Physiology, Vol 252, Issue 4 C450-C453, Copyright © 1987 by American Physiological Society

ARTICLES

Pretranslational regulation of myoglobin gene expression

L. E. Underwood and R. S. Williams

We have used blot hybridization techniques and a specific anti-sense RNA probe to determine whether variation in myoglobin gene expression among mammalian striated muscles is attributable to pretranslational regulatory events. We observed that myoglobin mRNA was expressed to approximately 10- and 5-fold greater levels, respectively, in cardiac and soleus (slow-twitch, oxidative, skeletal) muscles of adult rabbits than in tibialis anterior (fast-twitch, glycolytic, skeletal) muscles. Furthermore, when oxidative capacity of tibialis anterior muscles was increased by 21 days of indirect electrical stimulation, a model of exercise conditioning, myoglobin mRNA content increased approximately 15-fold. We conclude that pretranslational mechanisms are important in regulation of myoglobin gene expression in mammalian muscles.


This article has been cited by other articles:


Home page
 J. Exp. Biol.Home page
G. A. Ordway and D. J. Garry
Myoglobin: an essential hemoprotein in striated muscle
J. Exp. Biol., September 15, 2004; 207(20): 3441 - 3446.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
M. Vogt, A. Puntschart, J. Geiser, C. Zuleger, R. Billeter, and H. Hoppeler
Molecular adaptations in human skeletal muscle to endurance training under simulated hypoxic conditions
J Appl Physiol, July 1, 2001; 91(1): 173 - 182.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
W. G. Campbell, S. E. Gordon, C. J. Carlson, J. S. Pattison, M. T. Hamilton, and F. W. Booth
Differential global gene expression in red and white skeletal muscle
Am J Physiol Cell Physiol, April 1, 2001; 280(4): C763 - C768.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
P. D. Neufer, G. A. Ordway, and R. S. Williams
Transient regulation of c-fos, alpha B-crystallin, and hsp70 in muscle during recovery from contractile activity
Am J Physiol Cell Physiol, February 1, 1998; 274(2): C341 - C346.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Z. Yan, A. L. Serrano, S. Schiaffino, R. Bassel-Duby, and R. S. Williams
Regulatory Elements Governing Transcription in Specialized Myofiber Subtypes
J. Biol. Chem., May 11, 2001; 276(20): 17361 - 17366.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online