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Am J Physiol Cell Physiol (June 17, 2009). doi:10.1152/ajpcell.00256.2009
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Submitted on June 15, 2009
Accepted on June 15, 2009

A New Role for Satellite Cells: Control of Reinnervation After Muscle Injury by Semaphorin 3A

Linda K. McLoon1*

1 University of Minnesota

* To whom correspondence should be addressed. E-mail: mcloo001{at}umn.edu.

Tatsumi and colleagues demonstrate for the first time that semaphorin is expressed by satellite cells from skeletal muscle, and satellite cells respond to hepatocyte growth factor by significanly up-regulating this secretion. Semaphorin can play may roles in tissues, and the possible functions of semaphorin in regenerating muscle are discussed.






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